Highflowoxygenandriskofmortalityinpatientswithasuspectedacutecoronarysyndrome:pragmatic,clusterrandomised,crossovertrial
在疑诊急性冠状动脉综合征的患者中使用高流量吸氧与死亡风险的关系：实用性、整群随机、交叉试验
OBJECTIVES
Todeterminetheassociationbetweenhighflowsupplementaryoxygenand30daymortalityin
patientspresentingwithasuspectedacutecoronarysyndrome(ACS).
研究在疑似急性冠脉综合征（ACS）患者中高流量吸氧与30天死亡率之间的关系。
METHODS
DESIGN
Pragmatic,clusterrandomised,crossovertrial.
SETTING
FourgeographicalregionsinNewZealand.
PARTICIPANTS
patientswithsuspectedorconfirmedACSincludedintheAllNewZealandAcuteCoronarySyndromeQualityImprovementregistryorambulanceACSpathwayduringthestudyperiods.patientsweremanagedusingthehighoxygenprotocolandweremanagedusingthelowoxygenprotocol.FinaldiagnosisofSTelevationmyocardialinfarction(STEMI)andnon-STEMIweredeterminedfromtheregistryandICD-10dischargecodes.
INTERVENTIONS
Thefourgeographicalregionswererandomlyallocatedtoeachoftwooxygenprotocolsinsixmonthblocksovertwoyears.Thehighoxygenprotocolre